Synthesis of some benzo[d]thiazole derivatives via Suzuki cross-coupling reaction
DOI:
https://doi.org/10.56764/hpu2.jos.2022.1.1.60-65- Keywords:
- benzo[d]thiazole
- Suzuki reaction
- microwave oven
Abstract
In this study, 5 benzo[d]thiazole (3a-3e) derivatives were successfully synthesized in 2 steps through Suzuki cross-coupling reaction from 2-(4-bromophenyl)benzo[d]thiazole (2) and arylboronic acid derivatives with a fairly high yield of 80-95%.These compounds’ structure was determined through NMR and mass spectral analysis. Besides, The key compound 2 was synthesized with a domestic microwave oven which helps to save cost and time in the synthesis process.
In this study, 5 benzo[d]thiazole (3a-3e) derivatives were successfully synthesized in 2 steps through Suzuki cross-coupling reaction from 2-(4-bromophenyl)benzo[d]thiazole (2) and arylboronic acid derivatives with a fairly high yield of 80-95%.These compounds’ structure was determined through NMR and mass spectral analysis. Besides, The key compound 2 was synthesized with a domestic microwave oven which helps to save cost and time in the synthesis process.
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